Lymphedema is an abnormal buildup of fluid that causes swelling, most often in the arms or legs, but can affect any body region. The condition develops when lymph vessels or lymph nodes are under-developed, damaged or removed. It also can be related to vascular dysfunctions. It is a chronic, progressive condition that places patients at risk for enlarged limbs and skin infections. While there is not cure, lymphedema can be managed with proper care and complete decongestive therapy.