What Is Asclera®?

legs are injections of Asclera
60 year old female after two injections of Asclera for spider veins (Click to view larger)

Asclera® (polidocanol) Injection is a prescription medicine that is used in a procedure called sclerotherapy and is administered by a healthcare provider to treat two types of veins:


  • Uncomplicated spider veins (very small varicose veins ≤ 1 mm in diameter)
  • Uncomplicated small varicose veins (1 to 3 mm in diameter) known as reticular veins

How Does Asclera® Work?

Asclera® is a sclerosing agent that is injected into the vein. It works by damaging the endothelium, the cells lining the inside of blood vessels. This causes blood platelets and cellular debris to attach to the lining of the vessels; eventually, cellular debris and platelets cause the blood vessel to clot. Over time, the clotted vein will be replaced with tissue.

Patient Satisfaction

  • On average, 87% of patients were satisfied or very satisfied with their Asclera® treatment
  • Patients were significantly more satisfied with Asclera® than with either sodium tetradecyl sulfate (STS) or placebo (p<0.0001)

Post Injection Care

  • Patient should keep the pressure dressings in place the day of injections and should continue continuous thigh-high compressions for a week.
  • You are encouraged to walk the next 15-20 minutes post treatment. After that point, continue to wear compression garments for the next 2-3 days (5-7days for reticular veins) and continuously then for the 2-3 weeks while awake when up and active.
  • Patient may then return to office in one month for reevaluation and possible further treatment.


Pricing varies depending on area being treated. Average cost is $250-500 per treatment.