Springfield Clinic’s physicians have conducted clinical trials for over 50 years across numerous medical specialties. To date, the Clinical Research Department has conducted more than 400 clinical trials and continues research activities today. Search the table below to review our current clinical trials, investigators, and medical conditions under study.

Please contact us if you have additional questions about Springfield Clinic’s Clinical Research Department or current clinical trial activities.

Condition Principal Investigator Description
Ankylosing Spondylitis Robert Trapp, MD A study to compare Cosentyx 150mg vs. 300mg in adults with Ankylosing Spondylitis
Breast Cancer Preet Singh, MD Long-term follow up of women with Early-Stage HER-2/neu Overexpressed/Amplified Breast Cancer previously treated with Trastuzumab followed by Neratinib (IN FOLLOW UP)
C-difficile Steven O'Marro, MD Comparison of ridinilazole to vancomycin treatment for Clostridium difficile infection
C-difficile Steven O'Marro, MD A Phase 3 study of SER109 (Ecobiotic Drug) to reduce recurrence of C-diff infection in adults who have received antibiotic treatment for recurrent C-diff infection.
Diabetic Retinopathy Ramanath Bhandari, MD Intravitreous Anti-Vascular Endothelial Growth Factor Treatment for Prevention of Diabetic Retinopathy (Enrollment Closed)
Distal Tibial Fractures Matthew Gardner, MD Observational Study of Patients with Distal Tibial Fractures Requiring Surgical Intervention with Locked Plating (Enrollment Closed)
Diabetic Macular Edema Ramanath Bhandari, MD Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of DME
Heart Failure Ish Singla, MD A study of Vericiguat in Patients with Heart Failure with Reduced Ejection Fraction (Enrollment Closed)
Hip Fracture Matthew Gardner, MD N-Force screws augmented with N-Force Blue in Proximal Femur Fractures
Prostate Cancer David Lieber, MD Study comparing the occurrence of Major Adverse Cardiovascular Events in patients receiving Firmagon or Lupron for Prostate Cancer