Springfield Clinic Service Area consists of the following Illinois counties, including: Sangamon, Macoupin, Logan, Mason, Menard, Cass, Christian, Montgomery, Greene, Scott, Morgan and Macon, serving a metropolitan area of over 400,000 residents.

Springfield Clinic Occupational Medicine/Worker's Compensation Injury Management Service locations include: Lincoln and Sherman to the North, Decatur and Taylorville to the East, Carlinville, Hillsboro, Gillespie and Mt. Olive to the South, and Jacksonville to the West, together with 23 service sites in the greater Springfield area.