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Clinical Research Studies

Clinical trials are always underway at Springfield Clinic, in a number of medical specialties. Not all new medicines work, and there is no way to know their effectiveness in treating or curing disease unless clinical trials are performed. To that end, the Clinical Research Department works closely with the pharmaceutical companies, who are pioneering the new treatments, to get involved with the most innovative and promising therapies that have the potential to benefit our patients.

If you are considering participating in a clinical trial, it may be because you are affected by a specific health condition or because a loved one is affected. To find out what opportunities might be available to your or your family members, please find our list of current trials and the medical condition, or “indication,” being studied. We invite you to check back frequently as we have many upcoming studies as well. You may also be interested in those studies that are now closed to enrollment, which can be found under studies in follow-up and completed studies.

Studies Data

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ConditionPrincipal InvestigatorBrief Description
Colon CancerPeter Hofmann, MD

Comparison of the performance of EpiproColon Test and Fecal Immunochemical Testing in patients with Colorectal Cancer

Plaque PsoriasisSarah Dietrich, MD

Observational registry to assess long term safety of Humira for Chronic Plaque Psoriasis

Community Acquired PneumoniaMark Weaver, MD

Evaluation of an Oral Nutritional Supplement in patients > 55years that are hospitalized with Pneumonia

Aspergillosis Donald Graham, MD

Isavuconazole vs Voriconazole in treatment of non-chronic Aspergillus Fungal Infections

CandidemiaDonald Graham, MD

Use of Isavuconazole vs Caspofungin followed by Voriconazole for systemic Candidiasis Infections 

Complicated Skin InfectionsDonald Graham, MD

Single dose IV Oritavancin vs 7-10day IV Vancomycin for treatment of Acute Bacterial Skin and Skin Structure Infections

Clostridium difficileDonald Graham, MD

A single infusion of  Human Monoclonal Antibody(s) to C-diff toxin in order to determine efficacy in preventing recurrence when combined with standard antibiotic therapy

Complicated Intra-abdominal InfectionsDonald Graham, MD

Intravenous CXA-201 (given with Metronidazole) vs. Meropenem in patients with Complicated Intra-abdominal Infections

Head & Neck CancerTomasz Srokowski, MD

A study of Cetuximab (in combination with cisplatin or carboplatin and 5-FU) in patients with recurrent or metastatic Head & Neck Cancer

Lung CancerTomasz Srokowski, MD

Study of Docetaxel and Ramucirumab in the treatment of Stage IV Non-small cell Lung Cancer following disease progression after 1 prior Platinum-based therapy

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